Oxygenation-sensitive cardiovascular magnetic resonance
Identifieur interne : 000D11 ( Main/Exploration ); précédent : 000D10; suivant : 000D12Oxygenation-sensitive cardiovascular magnetic resonance
Auteurs : Matthias G. Friedrich [Canada] ; Theodoros D. Karamitsos [Royaume-Uni]Source :
- Journal of Cardiovascular Magnetic Resonance [ 1097-6647 ] ; 2013.
Abstract
Oxygenation-sensitive cardiovascular magnetic resonance (CMR) is a non-contrast technique that allows the non-invasive assessment of myocardial oxygenation. It capitalizes on the fact that deoxygenated hemoglobin in blood can act as an intrinsic contrast agent, changing proton signals in a fashion that can be imaged to reflect the level of blood oxygenation. Increases in O2 saturation increase the BOLD imaging signal (T2 or T2*), whereas decreases diminish it. This review presents the basic concepts and limitations of the BOLD technique, and summarizes the preclinical and clinical studies in the assessment of myocardial oxygenation with a focus on recent advances. Finally, it provides future directions and a brief look at emerging techniques of this evolving CMR field.
Url:
DOI: 10.1186/1532-429X-15-43
PubMed: 23706167
PubMed Central: 3681671
Affiliations:
- Canada, Royaume-Uni
- Alberta, Angleterre, Oxfordshire
- Calgary, Oxford
- Université d'Oxford, Université de Calgary
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Friedrich</name><affiliation wicri:level="1"><nlm:aff id="I1">Montreal Heart Institute, Departments of Cardiology and Radiology, Université de Montréal, Montreal, QC, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Montreal Heart Institute, Departments of Cardiology and Radiology, Université de Montréal, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="I2">Departments of Cardiac Sciences and Radiology, University of Calgary, Calgary, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Departments of Cardiac Sciences and Radiology, University of Calgary, Calgary</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Karamitsos, Theodoros D" sort="Karamitsos, Theodoros D" uniqKey="Karamitsos T" first="Theodoros D" last="Karamitsos">Theodoros D. 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Friedrich</name><affiliation wicri:level="1"><nlm:aff id="I1">Montreal Heart Institute, Departments of Cardiology and Radiology, Université de Montréal, Montreal, QC, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Montreal Heart Institute, Departments of Cardiology and Radiology, Université de Montréal, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="I2">Departments of Cardiac Sciences and Radiology, University of Calgary, Calgary, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>Departments of Cardiac Sciences and Radiology, University of Calgary, Calgary</wicri:regionArea><orgName type="university">Université de Calgary</orgName><placeName><settlement type="city">Calgary</settlement><region type="state">Alberta</region></placeName></affiliation></author><author><name sortKey="Karamitsos, Theodoros D" sort="Karamitsos, Theodoros D" uniqKey="Karamitsos T" first="Theodoros D" last="Karamitsos">Theodoros D. Karamitsos</name><affiliation wicri:level="4"><nlm:aff id="I3">Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author></analytic><series><title level="j">Journal of Cardiovascular Magnetic Resonance</title><idno type="ISSN">1097-6647</idno><idno type="eISSN">1532-429X</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Oxygenation-sensitive cardiovascular magnetic resonance (CMR) is a non-contrast technique that allows the non-invasive assessment of myocardial oxygenation. It capitalizes on the fact that deoxygenated hemoglobin in blood can act as an intrinsic contrast agent, changing proton signals in a fashion that can be imaged to reflect the level of blood oxygenation. Increases in O<sub>2</sub> saturation increase the BOLD imaging signal (T2 or T2*), whereas decreases diminish it. This review presents the basic concepts and limitations of the BOLD technique, and summarizes the preclinical and clinical studies in the assessment of myocardial oxygenation with a focus on recent advances. 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Holloway</name></author><author><name sortKey="Robson, Md" uniqKey="Robson M">MD Robson</name></author><author><name sortKey="Jerosch Herold, M" uniqKey="Jerosch Herold M">M Jerosch-Herold</name></author><author><name sortKey="Watkins, H" uniqKey="Watkins H">H Watkins</name></author><author><name sortKey="Neubauer, S" uniqKey="Neubauer S">S Neubauer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Friedrich, Mg" uniqKey="Friedrich M">MG Friedrich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bauer, Wr" uniqKey="Bauer W">WR Bauer</name></author><author><name sortKey="Nadler, W" uniqKey="Nadler W">W Nadler</name></author><author><name sortKey="Bock, M" uniqKey="Bock M">M Bock</name></author><author><name sortKey="Schad, Lr" uniqKey="Schad L">LR Schad</name></author><author><name sortKey="Wacker, C" uniqKey="Wacker C">C Wacker</name></author><author><name sortKey="Hartlep, A" uniqKey="Hartlep A">A Hartlep</name></author><author><name sortKey="Ertl, G" uniqKey="Ertl G">G Ertl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, X" uniqKey="Zhou X">X Zhou</name></author><author><name sortKey="Tsaftaris, Sa" uniqKey="Tsaftaris S">SA Tsaftaris</name></author><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y Liu</name></author><author><name sortKey="Tang, R" uniqKey="Tang R">R Tang</name></author><author><name sortKey="Klein, R" uniqKey="Klein R">R Klein</name></author><author><name sortKey="Zuehlsdorff, S" uniqKey="Zuehlsdorff S">S Zuehlsdorff</name></author><author><name sortKey="Li, D" uniqKey="Li D">D Li</name></author><author><name sortKey="Dharmakumar, R" uniqKey="Dharmakumar R">R Dharmakumar</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Canada</li><li>Royaume-Uni</li></country><region><li>Alberta</li><li>Angleterre</li><li>Oxfordshire</li></region><settlement><li>Calgary</li><li>Oxford</li></settlement><orgName><li>Université d'Oxford</li><li>Université de Calgary</li></orgName></list><tree><country name="Canada"><noRegion><name sortKey="Friedrich, Matthias G" sort="Friedrich, Matthias G" uniqKey="Friedrich M" first="Matthias G" last="Friedrich">Matthias G. Friedrich</name></noRegion><name sortKey="Friedrich, Matthias G" sort="Friedrich, Matthias G" uniqKey="Friedrich M" first="Matthias G" last="Friedrich">Matthias G. Friedrich</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Karamitsos, Theodoros D" sort="Karamitsos, Theodoros D" uniqKey="Karamitsos T" first="Theodoros D" last="Karamitsos">Theodoros D. Karamitsos</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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